What Are The Main Stages of Preclinical Drug Development?

A drug development project needs to go through various stages at a drug discovery CRO in order to deliver a drug that is not only efficacious but safe too while meeting all regulatory requirements. Preclinical drug development is an early stage that is crucial to define the course of such projects.

Generally, drug discovery chemists in India take a pool of drug compounds into consideration while starting their drug discovery program. Scientists at drug discovery CROs need to identify and segregate the promising ones from that pool. The promising drug compounds must pass through three crucial preclinical developmental phases for approval.

Important Stages During Target & Drug Candidate Identification:

You must be feeling curious to know a little more about the preclinical development solutions offered by contract research organizations in India. Drug discovery needs expert services from different areas of chemistry and biology. Let us mention and elaborate on the three primary stages of the target and drug candidate identification phase of drug development. 

1. Molecular Level Research: This stage of preclinical drug research involves research and observational studies to determine the molecular and cellular mechanisms of the disease of interest. It provides remarkable insights for the therapeutic drugs that function as a framework for the identification of new drug targets. 

2. Identify Relevant Targets: Target identification and characterization is a vital part of preclinical research and it begins with finding the function of a possible therapeutic target. Gene or protein is the prominent kinds of targets. Then, their mechanism of disease is determined. After identification, drug discovery experts proceed to understand the characterization of the molecular mechanisms addressed by the target.

3. Identify Drug Candidates: Identification of apt chemical compounds provides an improved understanding of their therapeutic effect along with the possible adverse effects. This stage helps drug discovery CRO in accelerating and de-risking drug discovery projects. Scientists get to know the most potent interactions for further pre-clinical evaluation both in cell line models as well as patient-derived material.

Integral Biosciences Is Renowned For Preclinical Drug Development Solutions

Are you looking for reliable drug discovery chemists in India? Are you searching for an experienced team for outsourcing your drug discovery projects, especially for preclinical research? If yes, then there is no need to look beyond Integral Biosciences.

Integral Biosciences is the leading preclinical research organization in India. It has delivered premium quality drug discovery services for over 13 years and is renowned for its specialty in oncology and CNS based drug discovery. Get in touch with the best experts of drug discovery at IBS today and accelerate your drug discovery projects.